Buy Tamoxiver (Tamoxifen) in Spain
NOLVADEX is an antagonist of estrogen receptors in breast tissue through its active metabolite, 4-hydroxytamoxifen -. In other tissues such as the endometrium, it behaves as an agonist, and thus can be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine (anti-estrogen) treatment for hormone receptor-positive breast cancer in premenopausal women and is also standard in postmenopausal women, although aromatase inhibitors are also frequently used in this setting. .
Some breast cancer cells need estrogen to grow. Estrogen binds to and activates the estrogen receptor on these cells. Tamoxifen is metabolized to compounds that also bind to estrogen receptors, but is not activated. Because of this competitive antagonism, tamoxifen acts like a broken key in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Therefore, the growth of breast cancer cells is blocked.
Tamoxifen is used to treat infertility in women with anovulatory disorders. A dose of 10-40 mg daily administered on days 3-7 of a woman's cycle. Also, a rare condition occasionally treated by tamoxifen is retroperitoneal fibrosis.
Effects of Tamoxiver (Tamoxifen)
Tamoxifen is used to prevent estrogen-related gynecomastia, which results in elevated estrogen levels. It is taken as a preventative measure in small doses, or used at the onset of any symptoms, eg nipple pain/tenderness.Other medications are taken for similar purposes, such as clomiphene citrate and anti-aromatase drugs that are used to try to avoid hormone-related side effects. Tamoxifen is also sometimes used to treat or prevent gynecomastia in sex offenders undergoing temporary chemical castration.
In bodybuilding Spain, Nolvadex (Tamoxifen Citrate) is used as an anabolic steroid cycle medication in secondary and recovery or post cycle anabolic steroid therapy.
Tamoxiver (Tamoxifen) Online Price UK
It is important to start a PCT once you have finished a steroid cycle to avoid a dramatic loss of mass gained. To the question of when to start a PCT depends on the type of steroid that have been used. If the cycle consists of orals, which have relatively the least effect on the body, it is advisable to start immediately. Some say that PCT can be started as early as the last day of the steroid cycle. If water-based injectable or short-acting esters, PCT is recommended 4-7 days after the last injection. In the case of long-acting esters, this should be approximately 10 to 14 days after the last injection.
Tamoxiver (Tamoxifen) Side Effects
A secondary benefit of tamoxifen is that it prevents bone loss by acting as an agonist for estrogen receptors on these types of cells. Thus, by inhibiting osteoclasts, which prevents osteoporosis. When tamoxifen Spain was launched as a drug, it was thought that tamoxifen could act as an antagonist of estrogen receptors in all tissues, including bone, and therefore it was feared that it would contribute to osteoporosis. Therefore, it is very surprising that the opposite effect was observed clinically.Thus, the tissue-selective action of tamoxifen has led to the formulation of the concept of the selective estrogen receptor modulator (SERM). In contrast, tamoxifen appears to be associated with bone loss in premenopausal women who continue to menstruate after adjuvant chemotherapy.
Side effects are few and mild with this drug. Nausea, vomiting, and hot flashes may be experienced by Nolvadex users.
High Dosage can prevent the natural production of testosterone by the testicles. In addition, a high dosage can be counterproductive, and that instead of lowering estrogen, it increases levels. This is a consequence when the adrenal glands are overly stimulated to produce the prohormone dehydroepiandrosterone or DHEA. DHEA changes into estrogen.