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This drug is a powerful anti-estrogen drug. It is designed for use in estrogen-dependent tumors in breast cancer. Steroid users take Nolvadex to prevent the effects of estrogen in the body. This estrogen is most often the result of the aromatizing effect of the steroid. It can help prevent edema, gynecomastia, and female pattern fat distribution, which can occur when a man's estrogen levels are too high. Also these effects can occur when androgen levels are too low, making estrogen the predominant hormone. This can occur when endogenous androgens have been suppressed by prolonged use of exogenous steroids in combination with cutting these exogenous sources. Nolvadex works by competitively binding to estrogen target sites such as the breast.
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This drug is not toxic nor have any side effects been seen in athletes using the drug as an anti-estrogen. This drug is the most popular anti-estrogen among anabolic steroid users at the moment. Although this drug is not 100% effective for everyone, it does seem to exhibit a certain level of effectiveness for everyone. It works so well for some bodybuilders, that you can take anabolic steroids like Dianabol or Anadrol right to a contest as long as you stack it with Nolvadex. It would be wiser to take this drug in conjunction with any steroid cycle. Most reported a dose of 10mg to 20mg daily did the job. Availability of Nolvadex has been just on the black market.
Nolvadex is very similar to Clomid, it behaves the same in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid.The two molecules are also very similar in structure.
It is not correct that Nolvadex lowers estrogen levels, rather it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, makes the receptor do nothing.
The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders Spain have been excellent results while using Nolvadex. The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction in IGF-1 (individuals using anabolic steroids not studied) from Nolvadex use. Therefore, Dan Duchaine reported that it reduces IGF-1 and thus reduces gains. However, if this effect exists, it must be very slight, due to the excellent gains many have made, and the fact that no one has noticed anything from Clomid, which has the same activity profile.
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However, I would not be surprised if one were to tell a steroid user that Clomid reduced their gains, they would immediately become afraid that Clomid reduced their gains (please note that the person I have never heard talk about has realized this). They have not been deceived, however, he did not draw this conclusion from the results of it. But if an authority publishes that such an effect occurs, whether it is the case or not, it can become self-fulfilling by user polarization.
The fact that Nolvadex reduces water retention may result in the user agreeing that gains are less, as weight gain is less, thus reinforcing the bias. Many bodybuilders take 10 to 20 mg of Nolvadex each day for the last month before a bodybuilding contest to help reduce water retention and increase muscle hardness.